Just like the rest of our skin, the lips are made up of three layers of cells: the outermost layer of mostly dead cells, known as the stratum corneum, the epidermis and the dermis, which sits below it.
Nicotine causes narrowing of the blood vessels in the outermost layers of the skin, while the chemicals in tobacco smoke damage collagen and elastin, fibres which give the skin its elasticity.
The outermost box is lined with ceramic fiber paper.
A planet, possibly four times the mass of Jupiter and with a lunar system, could be lurking in our solar system's outermost area, two US scientists theorize.
On a sunny day , David went to the outermost outskirts .
Abigail Adams (1744 - 1818), letter to John Adams, 1774 I've arrived at this outermost edge of my life by my own actions.
